We perform research to better understand blood vessel formation and fundamental mechanisms of cell signaling and tumor growth. To this end, a large part of our work is to create new and better methods to study cells as they communicate and migrate.
In our lab,we develop new microfluidic assays that we use to perform research to better understand how cells of the vascular system and cancer cells secrete factors in a process called exocytosis (1) and how this affects signaling and communication between cells (2). We also study how signaling receptors at the cell surface are recycled within cells (3), and finally how some of the molecules affecting the communication between cells are produced (4). We are also interested in how these events affect directed cell migration, a process called chemotaxis.